Curcuma Xanthorrhiza Essential Oil (Xanthorrhizol)

Conclusion: These results suggest that the xanthorrhizol could be an attractive candidate as a natural antimicrobial compounds in oral hygiene products and appear to warrant clinical investigation.

Results: Results showed that the Bamboo Salt toothpaste required 4%, compared to 2% Colgate Total in order to obtain the inhibitory concentration. And the LG mouthrinse having the inhibitory effect at 1% of concentration is superior to not only to the Colgate Total Plax at 30% but also Listerine at 50%.

Methods: The Bamboo Salt toothpaste(LG Household & HealthCare) containig 0.3% xanthorrhizol was compared with commercially available Colgate Total (Colgate and Palmolive) with 0.3% of triclosan, in terms of their antimicrobial capacity. The solid particles in slurry solutions of the each toothpaste was separated and then, the supernatants were employed as test materials. The test materials were serially diluted with distilled water and one part of each dilution was mixed with nine part of inoculum of S.mutans (10⁶ cell/ml) , giving final concentrations of test materials of 8, 4 , 2, 1,1, 0.5, 0.25, 0.12%, respectively. After 1 minute exposure of cells to the test materials, aliquots of 10ul of test suspension were spread onto THB agar plates using a loop. The lowest concentrations giving less than 100 CFUs were determined. For the mouthrinse study, commercially available Colgate Plax with 0.03% triclosan, Listerine with essential oil as active ingredients, and an experimental LG Mouth rinse containing 0.03% xanthorrhizol were employed and compared with the same procedure except the final concentrations of mouthrinse 50, 30,10,7, 5,3, 1%, respectively.

Objectives: Xanthorrhizol,a major terpenoid found in only Curcuma xanthorrhiza known as traditional Indonesian folk medicine, have a stronger activity than synthetic triclosan against oral bacteria including Streptococcus mutans, sobrinus, and Porphyromonas. gigivalis . The aim of this study was to determine whether toothpastes and mouthrinse containing xanthorrhizol could inhibit the growth of Streptococcus mutans 10449.

¹, M.M. KIM¹, S.N. KIM¹, H.D. KIM¹, Y.H. KIM¹, M.J. RANG¹, H.J. AHN¹, and J.K. HWANG², ¹(LG Household and Healthcare Ltd./Research Park, Taejeon, South Korea, ²Yonsei University, Seoul, South Korea

Evaluation of xanthorrhizol as a natural antimicrobial agent for oral hygiene products

Curcuma Xanthorrhiza esential oil contains xanthorrhizol which is very good for oral health (anti bacterial) and Dry Scalp.