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Forming of the system response depends on the influence of the mentioned factors and individual genotypic features. This process has non episodic, but permanent nature, i.e. indissolubly connected with the vital activity of the organism and is the basis f the process of stable non-balance, according E.Bauer (1935). The possibility to respond to both strong and weak stimuli should be emphasized too. From this point, stress response, described by G.Selie (1960), is only a particular manifestation of this system response to the very strong stimulus.Investigations, carring out in the Institute of the Air and Space Medicine, allow to establish common biologic regularities of the discrete changes of blood composition arisen from the influence of various agents modified by different doses and dynamic characteristics (Pic.1). On basis of received regularities the scale of the organism adaptive condition was formed. Adaptive level and coefficient of reaction are the indices of this scale (Pic.2). Zero level the level, when the blood indices, taking into consideration by revealed regularties, have minimal values. Adaptive level represents reccurent phases of blood composition changes. Coefficient of reaction is the formalized index of blood composition changes within every phase.

, , , , .

- underlying localization of the stimulus application (central nervous system, respiratory tract, gastrointestinal tract, skin and others).

- relative amplitude-temporal dynamic stimulus characteristics (exposure time, rate of rise, coming out on plateau, descent rate, cumulative dose);

- relative power or intensity of the affecting stimulus;

Human life is closely associated with the influence of different stimuli: gravitation, atmosphere pressure, temperature, electromagnetic radiation and other factors. The influence of stimuli first of all leads to the increase of organism tonus and, along with it; permanent changes take place under the influence of the environment. However, the organism systems selectively respond to every stimulus from the whole aggregate of them. The investigations show that the main factors in the organism response to this or another stimulus are:

The last approach to the determination of the adaptation obviously doesnt only reflect the main point of the phenomenon, but also has a very distinct applied orientation. At the same time the term balance cant adequately reflect the dynamic changes in the organism, permanent violations of the balance, directed to keep the homeostasis. That is why it would be more correct to say about stable non-balance, the main point of which E.Bauer revealed in his work (1935). The conception of adaptation in such a way is the basis for the forming of the adaptive response and adaptation development.

" the condition of the balance between the organism and the environment.

" the process of the organism adaptation to the environmental conditions;

" the result of the evolutional process of adaptation development;

Using the term adaptation, many authors mean different aspects of the interaction of living organism with the environment:

The attempts to use different indices, characterizing human adaptive abilities, in the interests of applied medicine, have found their reflection in the transactions of famous scientists (Agadjanyan, 1997; Anohin, 1962; Vasilivskiy, 1977, Kaznacheev, 1980; Kopanev, Vlasov,1982; Kochetkov, 1990; Medvedev, 1984; Meerson, 1981, 1991; Orbely, 1961; Slonim, 1964; and many others).

The basis of the adaptive organism condition estimation method

The basis of the adaptive organism condition estimation method

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