Sell paclitaxel ycgcsale58@yccreate.com @China (Mainland)

Paclitaxel ycgcsale58@yccreate.com

Molecular Formula: C47H51O14

Molecular Weight: 853.9182

Cas Number: 33069-62-4

Appearance: white powder

Mesh: 80 mesh

Active ingredient content: 97-99% HPLC

Heavy Metal: <2PPM

Loss on drying: <1%

Ash: 0.2%

Melting point: 213-215 ° C

Specific rotation: -49 ~ -55

Function and use: Department of paclitaxel from the

bark of the natural plant extract of Taxus diterpenoid

alkaloid monomer compounds found in recent years, new mechanisms

of cytotoxic anticancer drugs, is the world's The most effective

new anti-microtubule drug, its promotion of tubulin polymerization by

inhibiting the depolymerization of tubulin to maintain stability,

and inhibition of cell mitosis. In vitro experiments show that taxol has significant

radiosensitization, May be to stay on the radiation-sensitive

cells G2 and M phase.Unique is that cancer does not affect the synthesisof

DNA and RNA, or damage DNA molecules, which selectively promotes the rapid

aggregation of tubulin into micro- Tube, combined to inhibit microtubule

depolymerization of microtubules, thus affecting the spinning cone,

inhibit cancer cell mitosis; or the payment of microtubule polymerization,

inhibition of microtubule depolymerization and inhibition of cell

division. Eggs on the clinical Ovarian cancer, breast cancer,

non-small cell lung cancer, head and

neck cancer such as a significant effect.

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Post by Nancy Zhhou Chemicals @2013-02-26 09:29:15

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