Sell name:pemetrexed disodium,150399-23-8(ycgcsale56@yccreate.com) @China (Mainland)

Name:pemetrexed disodium,150399-23-8(ycgcsale56@yccreate.com)

Cas No:150399-23-8 

MF:C20H21N5O6 

Use:antineoplastic 

Appearance:white powder

General introduction:Pemetrexed is a chemotherapy drug manufactured . Its indications are the treatment of pleural mesothelioma as well as non-small cell lung cancer.

Mechanism of action:Pemetrexed is chemically similar to folic acid and is in the class of chemotherapy drugs called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). By inhibiting the formation of precursor purine and pyrimidine nucleotides, pemetrexed prevents the formation of DNA and RNA, which are required for the growth and survival of both normal cells and cancer cells.