sell:terbinafine,78628-80-5(ycgcsale56@yccreate.com)
Name:terbinafine hcl
Cas No:78628-80-5
MF:C21H25N
Use:antifungal
Appearance:white powder
General introduction:
Terbinafine hydrochloride a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. As a generic it is sold under many names as
a generic medication in the United States, United Kingdom, Belgium and Switzerland.
Pharmacology:
Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and slightly soluble in water.
Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine
prevents conversion ofsqualene to lanosterol, ergosterol cannot be synthesized. This is thought to change cell membrane permeability, causing fungal cell lysis.
Post by Agnes Jin Chemicals @2013-03-25 03:46:56