Purine nucleoside phosphorylase (also known as PNPase) is an enzyme (EC 2.4.2.1) involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine, in each case creating ribose phosphate. NP encodes the enzyme purine ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:35:54 ]
Phospholipase C is an enzyme with system name phosphatidylcholine cholinephosphohydrolase. This enzyme catalyses the following chemical reaction: a phosphatidylcholine + H2O↔ 1, 2-diacyl-sn-glycerol + phosphocholine. The bacterial enzyme is a zinc protein. It also acts on ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:35:23 ]
Glucose-6-phosphate isomerase is an enzyme that catalyzes the conversion of glucose-6-phosphate into fructose 6-phosphate in the second step of glycolysis. The human variant of this enzyme is encoded by the GPI ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:34:51 ]
Oxaloacetate decarboxylase is a carboxy-lyase involved in the conversion of oxaloacetate into pyruvate. It is categorized under EC 4.1.1.3. In some bacteria this enzyme is a trimer, composed of alpha, beta and gamma subunits. The beta and gamma subunits are integral membrane ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:34:17 ]
Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:33:45 ]
Amine oxidases (AO) are enzymes that catalyze the oxidation of a wide range of biogenic amines including many neurotransmitters, histamine and xenobiotic amines. There are two classes of amine oxidases: flavin-containing (EC 1.4.3.4) and copper-containing (EC 1.4.3.6). ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:32:56 ]
In enzymology, a lysophospholipase (EC 3.1.1.5) is an enzyme that catalyzes the chemical reaction: 2-lysophosphatidylcholine + H2O ↔ glycerophosphocholine + a carboxylate. Thus, the two substrates of this enzyme are 2-lysophosphatidylcholine and H2O, whereas its two products ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:30:57 ]
In enzymology, a lactate 2-monooxygenase (EC 1.13.12.4) is an enzyme that catalyzes the chemical reaction: (S)-lactate + O2 ↔ acetate + CO2 + H2O. Thus, the two substrates of this enzyme are (S)-lactate and O2, whereas its 3 products are acetate, CO2, and ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:29:30 ]
Glutamine synthetase (GS) (EC 6.3.1.2) is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine: Glutamate + ATP + NH3 → Glutamine + ADP + phosphate. Glutamine Synthetase uses ammonia ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:28:07 ]
In enzymology, a glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction: sn-glycerol 3-phosphate + O2↔ glycerone phosphate + H2O2. Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and O2, whereas its two products are ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:27:32 ]
In enzymology, a glycerophosphocholine phosphodiesterase (EC 3.1.4.2) is an enzyme that catalyzes the chemical reaction: sn-glycero-3-phosphocholine + H2O↔ choline + sn-glycerol 3-phosphate. Thus, the two substrates of this enzyme are sn-glycero-3-phosphocholine and H2O, ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:26:59 ]
The activity of glycerol kinase is found widely in nature. In microorganisms GK makes possible the utilization of glycerol as a carbon source. In mammals the enzyme represents a juncture of sugar and fat metabolism; The enzyme is important to the clinical chemist in the ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:26:24 ]
Glutamate dehydrogenase (GLDH) is an enzyme, present in most microbes and the mitochondria of eukaryotes, as are some of the other enzymes required for urea synthesis, that converts glutamate to α-ketoglutarate, and vice versa. In animals, the produced ammonia is usually used ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:25:50 ]
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is an cytosolic enzyme that catalyzes the chemical reaction: D-glucose 6-phosphate + NADP+↔ 6-phospho-D-glucono-1, 5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway (see image), a metabolic ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:25:16 ]
Glucose-6-phosphate dehydrogenase (G6PD or G6PDH) (EC 1.1.1.49) is an cytosolic enzyme that catalyzes the chemical reaction: D-glucose 6-phosphate + NADP+↔ 6-phospho-D-glucono-1, 5-lactone + NADPH + H+. This enzyme is in the pentose phosphate pathway (see image), a metabolic ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:24:40 ]
In enzymology, a NADPH dehydrogenase is an enzyme that catalyzes In enzymology, a NAD (P)H dehydrogenase (quinone) (EC 1.6.5.2) is an enzyme that catalyzes the chemical reaction NAD (P)H + H+ + a quinone↔ NAD (P)+ + a hydroquinone. The 4 substrates of this enzyme are NADH, ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:24:08 ]
In enzymology, a choline oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction choline + O2↔ betaine aldehyde + H2O2. Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:23:35 ]
Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:23:03 ]
Recombinant Cholesterol Oxidase belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in bile acid ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:22:27 ]
Sterol esterase belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is steryl-ester acylhydrolase. This enzyme participates in bile acid ...
Creative Enzymes [Chemicals] [Pharmaceutical Chemicals] [2015-10-22 11:21:47 ]
