Native Bacillus sp. Purine Nucleoside Phosphorylase

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Purine nucleoside phosphorylase (also known as PNPase) is an enzyme (EC 2.4.2.1) involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine, in each case creating ribose phosphate. NP encodes the enzyme purine nucleoside phosphorylase that together with adenosine deaminase (ADA) serves a key role in purine catabolism, referred to as the salvage pathway. Mutations in either enzyme result in a severe combined immunodeficiency (SCID). Confusingly, the same abbreviation (PNPase), is also used for another, otherwise unrelated, enzyme, namely Polynucleotide Phosphorylase.http://www.creative-enzymes.com/product/Native-Bacillus-Sp-Purine-Nucleoside-Phosphorylase_760.html

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  • Founded Year:2005
  • Address:45-1 Ramsey Road Shirley
  • Contact:Lisa Clara
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Native Microorganism Purine-nucleoside phosphorylase
Native Microorganism Purine-nucleoside phosphorylase

In enzymology, a purine-nucleoside phosphorylase (EC 2.4.2.1) is an enzyme that catalyzes the chemical reaction: purine nucleoside + phosphate ↔ purine + alpha-D-ribose 1-phosphate. Thus, the two substrates of this enzyme are purine nucleoside and phosphate, whereas its two ...

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