There are two important signs of alcohol dependence: tolerance and withdrawal. First, prolonged exposure makes the body resistant to alcohol. As the body adapts to continue functioning, tolerance increases and requires more alcohol to achieve the desired effect. . If a person experiences these symptoms but continues to drink to appease the discomfort, it is a clear and convincing sign that they need help. The specific scope of treatment used for inpatient alcohol rehabilitation may vary depending on the treatment center and the diverse needs of the client.