Actinomycin D

FOB Price
USD $280.00 / Piece
Place Of Origin
Hubei, China
Minimum Order
100
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days
Effective Oncology API Actinomycin D/Dactinomycin
CAS: 50-76-0

Quick Details:
Product Name Dactinomycin
Synonyms 3H-Phenoxazine-1,9-dicarboxamide, 2-amino-N,N'-bis[hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-4,6-dimethyl-3-oxo-; hbf 386; Lyovac cosmegen; Meractinomycin; Oncostatin K; X 97; Actactinomycin A IV; Actinomycin 7; Actinomycin AIV; Actinomycindioic D acid, dilactone; Actinomycin C1; actinomycin cl; Actinomycin D; (-)-actinomycin d; actinomycin i; Actinomycin I1; Actinomycin IV; Actinomycin-[threo-val-pro-sar-meval]; Actinomycin X 1; actinomycin x i; actinomyein-theo-val-pro-sar-meval; ACTO-D; AD; Dilactone actinomycindioic D acid; Dilactone actinomycin D acid; C1; Cosmegen; Dactinomycin D; dactinomyein d; 2-amino-4,6-dimethyl-3-oxo-N,N'-bis[2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-di(propan-2-yl)hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-3H-phenoxazine-1,9-dicarboxamide; 2-amino-4,6-dimethyl-3-oxo-N,N'-bis[2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxooctadecahydrocyclopenta[i][1,4,7,13]oxatriazacyclohexadecin-10-yl]-3H-phenoxazine-1,9-dicarboxamide; 2-amino-4,6-dimethyl-3-oxo-N,N'-bis[(6S,9R,10S,13R,18aS)-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-di(propan-2-yl)hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-3H-phenoxazine-1,9-dicarboxamide; ACTD
MF C62H86N12O16
MW 1255.417

Product Description:

Dactinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria. Actinomycin D can induce apoptosis in several cell lines such as lung and prostate cancer lines, and human blood lymphocytes, among others. This compound is also an RNA polymerase inhibitor. In studies it has been observed that Actinomycin D elevates p53 expression, leading to the increase of PUMAα/β (the p53 upregulated modulator of apoptosis protein; PUMA), and can also induce tumornecrosis factor-related apoptosis-inducing ligand (TRAIL)-induced caspase-dependent and -independent apoptosis.
FEATURED PRODUCT:

Wuhan Newbio Pharm-tech Co., Ltd.
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