Cisplatin

FOB Price
USD $280.00 / Piece
Place Of Origin
Hubei, China
Minimum Order
100
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days
Effective Anti Tumor Inhibitor API Cisplatin
(CAS 15663-27-1)

Chemical Information
Quick Details:
Cisplatin CAS :15663-27-1 Brand:NEWBIO
MW: Cl2H6N2Pt MSDS: Avaiable
MF : 300.05
Sample: Avaiable
Category: Oncology drug Min order: 10grams
Quality standard:USP29 /EP5 Place of Origin:China
Introduction Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung cancer, and ovarian cancer), lymphomas, and germ cell tumors.Cisplatin is particularly effective against testicular cancer; the cure rate was improved from 10% to 85%.
In addition, Cisplatin is used in Auger therapy.
Character Yellow or orange yellow crystals powder
Applications Pharmaceutical raw materials , Oncology drug
Product Description
Cisplatin is a potent platinum-based anti-neoplastic agent that is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The compound has also been shown to induce apoptosis through caspase-3 activation and XIAP expression. Also shown to cause immunosuppression which is thought to be followed by an increase in the host immune response. Platinated DNA adducts also enhance poisoning of DNA topoisomerase I by camptothecin (sc-200871). Cisplatin was the first member of a class of anticancer drugs, which now include carboplatin (sc-202093) and oxaliplatin (sc-202270), that form DNA adducts resulting in apoptosis; however, these molecules also bind other biological molecules such as enzymes which might play a role in their mechanism of action.
COA:
Analysis Test Specification Result
Description white crystalline powder,odorless Conforms
Solubility Easily soluble in water, unsoluble in ethanol Conforms
PH 6.0~7.5 6.9
Solution clarity and color solution should be clear and colorless Conforms

5'CMP 0.3% 0.0001
Related substances Simple impurity 0.0003

Total other impurity 0.001
Chloride 0.0005 Conforms
Ammonium 0.0005 Conforms
Fe 0.0001 Conforms
Phosphate 0.001 Conforms
Loss on drying ≤6.0%
Heavy metals 0.00002 Conforms
Arsenide 0.000001 Conforms
Bacterial Endotoxins 0.3EU/mg Conforms
Microbial Limit
Conforms
Assay(on dried basis) ≥98.0% 0.988
Conclusion: The results conform with CP2010


FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
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TriHydrate
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12 357336-20-0 Brivaracetam 36 63121-00-6 Oxaliplatin
13 842133-18-0 Canagliflozin 49 33069-62-4 Paclitaxel
14 928672-86-0 Canagliflozin HemiHydrate 37 137281-23-3 Pemetrexed Disodium
15 41575-94-4 Carboplatin 38 53123-88-9 Rapamycin
16 50935-04-1 Carubicin 50 135062-02-1 Repaglinide
17 288383-20-0 Cediranib 39 945667-22-1 Saxagliptin Hydrate
18 15663-27-1 Cisplatin 40 709031-78-7 Saxagliptin Hydrochloride
19 877399-52-5 Crizotinib 41 486460-32-6 Sitagliptin
20 171500-79-1 Dalbavancin 42 654671-77-9 Sitagliptin Phosphate Hydrate
21 114977-28-5 Docetaxel 44 85622-93-1 Temozolomide
22 148408-66-6 Docetaxel TriHydrate 45 477600-75-2 Tofacitinib
23 25316-40-9 Doxorubicin hydrochloride 46 540737-29-9 Tofacitinib Citrate
24 133040-01-4 Eprosartan 47 170791-09-0 Trityl Candesartan Cilexetil

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  • Founded Year:2015
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  • Contact:Jason Edwards
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