Product Quick Detail

FOB Price
USD $280.00 / Piece
Minimum Order
100
Place Of Origin
Hubei, China
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days

Hot Sell Small Molecular API Erlotinib
(CAS# 183321-74-6)

Chemical Information:
Product Name Erlotinib
Molecular Formula C22H23N3O4
Molecular Weight 393.44
Storage Store at -20°C
Targets EGFR
IC50 2 nM
Original Wuhan, China
Brand name NEWBIO
Purity 99%
Appearance White Powder
Package 100g/bag; 1KG/bag or as required
Shipping Fast and secure shipping by DHL,EMS,UPS, FedEx..
Shipping leading time Within 12 hours after receiving the payment
Payment Terms Western Union, Money Gram , T/T, Bitcon
MOQ 100g
Supply ability Mass stock

Description:
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.

Application:
At doses of 100 mg/kg, Erlotinib HCl completely prevents EGF-induced autophosphorylation of EGFR in human HN5 tumors growing as xenografts in athymic mice and of the hepatic EGFR of the treated mice. Erlotinib HCl (100 mg/Kg) inhibits H460a and A549 tumor models with 71 and 93% inhibition rate.
Erlotinib inhibits purified EGFR tyrosine kinase and EGFR autophosphorylation intact cells with 50% inhibition concentration IC50 values of 2 nmol/L and 20 nmol/L respectively. Erlotinib competes for the ATP-binding sits on the intracellular domain of EGFR resulting in the inhibition of downstream signaling pathway involved in angiogenesis, cell propagation and cell survival. Erlotinib concentration-dependently inhibits EGFR-mediated propagation signals transduction, displays prominent anti-tumor activity against neoplasms harboring EGFR expression and exhibits a tolerable toxicologic profile.

FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
S# CAS No. Product Name S# CAS No. Product Name
1 86639-52-3 7-Ethyl-10-Hydroxycamptothecin 25 183321-74-6 Erlotinib
2 154229-18-2 Abiraterone Acetate 26 183319-69-9 Erlotinib Hydrochloride
3 50-76-0 Actinomycin D 27 159351-69-6 Everolimus
4 106941-25-7 Adefovir 28 56296-78-7 Fluoxetine Hydrochloride
5 850140-72-6 Afatinib 29 184475-55-6 Gefitinib Hydrochloride
6 330784-47-9 Avanafil 30 136572-09-3 Irinotecan Hydrochloride
TriHydrate
7 319460-85-0 Axitinib 31 1441674-54-9 Ledipasvir(Acetone)
8 1421373-66-1 AZD-9291 (Mesylate) 32 191732-72-6 Lenalidomide
9 123524-52-7 Azelnidipine 33 21672 Methotrexate
10 863031-21-4 Azilsartan Medoxomil 34 76144-81-5 Mildronate
11 179324-69-7 Bortezomib 35 474645-27-7 Monomethyl Auristatin E
12 357336-20-0 Brivaracetam 36 63121-00-6 Oxaliplatin
13 842133-18-0 Canagliflozin 49 33069-62-4 Paclitaxel
14 928672-86-0 Canagliflozin HemiHydrate 37 137281-23-3 Pemetrexed Disodium
15 41575-94-4 Carboplatin 38 53123-88-9 Rapamycin
16 50935-04-1 Carubicin 50 135062-02-1 Repaglinide
17 288383-20-0 Cediranib 39 945667-22-1 Saxagliptin Hydrate
18 15663-27-1 Cisplatin 40 709031-78-7 Saxagliptin Hydrochloride
19 877399-52-5 Crizotinib 41 486460-32-6 Sitagliptin
20 171500-79-1 Dalbavancin 42 654671-77-9 Sitagliptin Phosphate Hydrate
21 114977-28-5 Docetaxel 44 85622-93-1 Temozolomide
22 148408-66-6 Docetaxel TriHydrate 45 477600-75-2 Tofacitinib
23 25316-40-9 Doxorubicin hydrochloride 46 540737-29-9 Tofacitinib Citrate
24 133040-01-4 Eprosartan 47 170791-09-0 Trityl Candesartan Cilexetil

ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment.
#2 Secure and discreet shipment.
#3 Various methods for your choice, like DHL/FedEx/SF-express.
​
OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
​
CONTACT US:
Telephone +86-027-87002705
Mobile +86-13277093700
newbiopharmtech
FaceBook Page https://www.facebook.com/newbiopharma/
Facebook Group https://www.facebook.com/groups/1739616069613416/
Website http://www.newbiopharm.com/
Online Store http://biocar.en.made-in-china.com/
​
If you want to source ...
#1 Pharmaceutical raw material,
#2 Oncology drug APIs,
#3 Antibiotics or fine chemicals,

We are a reliable manufacturer and supplier in China.
NEWBIO would like to ...
#1 We foucus on the high purity and high quality;
#2 We provide the raw materials at a good price;
#3 We have the best service and we are always there for you.

Please contact us for more infomation!!!
  • Country: China (Mainland)
  • Business Type:
  • Market:
  • Founded Year:2015
  • Address:
  • Contact:Jason Edwards
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