Original | Wuhan, China |
Brand name | NEWBIO |
Purity | 99% |
Appearance | White Powder |
Package | 100g/bag; 1KG/bag or as required |
Shipping | Fast and secure shipping by DHL,EMS,UPS, FedEx.. |
Shipping leading time | Within 12 hours after receiving the payment |
Payment Terms | Western Union, Money Gram , T/T, Bitcon |
MOQ | 100g |
Supply ability | Mass stock |
Description:
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl.
Application:
At doses of 100 mg/kg, Erlotinib HCl completely prevents EGF-induced autophosphorylation of EGFR in human HN5 tumors growing as xenografts in athymic mice and of the hepatic EGFR of the treated mice. Erlotinib HCl (100 mg/Kg) inhibits H460a and A549 tumor models with 71 and 93% inhibition rate.
Erlotinib inhibits purified EGFR tyrosine kinase and EGFR autophosphorylation intact cells with 50% inhibition concentration IC50 values of 2 nmol/L and 20 nmol/L respectively. Erlotinib competes for the ATP-binding sits on the intracellular domain of EGFR resulting in the inhibition of downstream signaling pathway involved in angiogenesis, cell propagation and cell survival. Erlotinib concentration-dependently inhibits EGFR-mediated propagation signals transduction, displays prominent anti-tumor activity against neoplasms harboring EGFR expression and exhibits a tolerable toxicologic profile.
FEATURED PRODUCT: Wuhan Newbio Pharm-tech Co., Ltd. |
S# | CAS No. | Product Name | S# | CAS No. | Product Name |
1 | 86639-52-3 | 7-Ethyl-10-Hydroxycamptothecin | 25 | 183321-74-6 | Erlotinib |
2 | 154229-18-2 | Abiraterone Acetate | 26 | 183319-69-9 | Erlotinib Hydrochloride |
3 | 50-76-0 | Actinomycin D | 27 | 159351-69-6 | Everolimus |
4 | 106941-25-7 | Adefovir | 28 | 56296-78-7 | Fluoxetine Hydrochloride |
5 | 850140-72-6 | Afatinib | 29 | 184475-55-6 | Gefitinib Hydrochloride |
6 | 330784-47-9 | Avanafil | 30 | 136572-09-3 | Irinotecan Hydrochloride TriHydrate |
7 | 319460-85-0 | Axitinib | 31 | 1441674-54-9 | Ledipasvir(Acetone) |
8 | 1421373-66-1 | AZD-9291 (Mesylate) | 32 | 191732-72-6 | Lenalidomide |
9 | 123524-52-7 | Azelnidipine | 33 | 21672 | Methotrexate |
10 | 863031-21-4 | Azilsartan Medoxomil | 34 | 76144-81-5 | Mildronate |
11 | 179324-69-7 | Bortezomib | 35 | 474645-27-7 | Monomethyl Auristatin E |
12 | 357336-20-0 | Brivaracetam | 36 | 63121-00-6 | Oxaliplatin |
13 | 842133-18-0 | Canagliflozin | 49 | 33069-62-4 | Paclitaxel |
14 | 928672-86-0 | Canagliflozin HemiHydrate | 37 | 137281-23-3 | Pemetrexed Disodium |
15 | 41575-94-4 | Carboplatin | 38 | 53123-88-9 | Rapamycin |
16 | 50935-04-1 | Carubicin | 50 | 135062-02-1 | Repaglinide |
17 | 288383-20-0 | Cediranib | 39 | 945667-22-1 | Saxagliptin Hydrate |
18 | 15663-27-1 | Cisplatin | 40 | 709031-78-7 | Saxagliptin Hydrochloride |
19 | 877399-52-5 | Crizotinib | 41 | 486460-32-6 | Sitagliptin |
20 | 171500-79-1 | Dalbavancin | 42 | 654671-77-9 | Sitagliptin Phosphate Hydrate |
21 | 114977-28-5 | Docetaxel | 44 | 85622-93-1 | Temozolomide |
22 | 148408-66-6 | Docetaxel TriHydrate | 45 | 477600-75-2 | Tofacitinib |
23 | 25316-40-9 | Doxorubicin hydrochloride | 46 | 540737-29-9 | Tofacitinib Citrate |
24 | 133040-01-4 | Eprosartan | 47 | 170791-09-0 | Trityl Candesartan Cilexetil |
ABOUT DELIVERY: #1 Products can be sent out within 24 hours after payment.
#2 Secure and discreet shipment.
#3 Various methods for your choice, like DHL/FedEx/SF-express.
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OUR COMMITMENT: #1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
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CONTACT US: Telephone | +86-027-87002705 |
Mobile | +86-13277093700 |
| newbiopharmtech |
FaceBook Page | https://www.facebook.com/newbiopharma/ |
Facebook Group | https://www.facebook.com/groups/1739616069613416/ |
Website | http://www.newbiopharm.com/ |
Online Store | http://biocar.en.made-in-china.com/ |
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If you want to source ...
#1 Pharmaceutical raw material,
#2 Oncology drug APIs,
#3 Antibiotics or fine chemicals,
We are a reliable manufacturer and supplier in China.
NEWBIO would like to ...
#1 We foucus on the high purity and high quality;
#2 We provide the raw materials at a good price;
#3 We have the best service and we are always there for you.
Please contact us for more infomation!!!