Cediranib

FOB Price
USD $280.00 / Piece
Place Of Origin
Hubei, China
Minimum Order
100
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days
Top Quality Small Molecular API Cediranib
(CAS: 288383-20-0)

Chemical Information
Product Name Gefitinib hydrochloride
Molecular Formula C22H25Cl2FN4O3
Molecular Weight 483.36
Storage Store at -20°C
Targets VEGFR-1/2/3 PDGFRβ RET
IC50 22/4/5.2nM 39nM 35nM

Description
The EGFR is a Mr 170,000 transmembrane glycoprotein with an external binding domain and an intracellular tyrosine kinase domain. Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.

Dosage
Administration of a 250-mg dose of gefitinib as a dispersion preparation by drink or nasogastric tube achieved a systemic exposure to gefitinib that was consistent with that achieved when gefitinib was administered as a whole tablet. No evidence of tolerability problems associated with the routes of administration studied was observed in these healthy volunteers.

COA:
Name: Gefitinib hydrochloride
CAS No.: 184475-55-6
Content: >99%
Appearance: A white,Crystalline Powder or colorless crystals
Formula: C22H25Cl2FN4O3
Molecular Weight 483.3633
Moisture: <1mg/mL
Loss on Drying: ≤0.2%
Residue on ignition: ≤0.1%
Ethanol: ≥11mg/mL
Stability: at -20°C 2 years
Solubility: DMSO ≥89mg/mL
Heavy Metals: ≤10PPM
Acidity or Alkalinity: Conform
Chloride: Conform
Readily Carbonizable Substances: Conform
Ordinary Impurities: Conform

FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
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TriHydrate
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15 41575-94-4 Carboplatin 38 53123-88-9 Rapamycin
16 50935-04-1 Carubicin 50 135062-02-1 Repaglinide
17 288383-20-0 Cediranib 39 945667-22-1 Saxagliptin Hydrate
18 15663-27-1 Cisplatin 40 709031-78-7 Saxagliptin Hydrochloride
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23 25316-40-9 Doxorubicin hydrochloride 46 540737-29-9 Tofacitinib Citrate
24 133040-01-4 Eprosartan 47 170791-09-0 Trityl Candesartan Cilexetil

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Cediranib
Cediranib

Top Quality Small Molecular API Cediranib (CAS: 288383-20-0) Chemical Information: Product Name Cediranib Molecular Formula C25H27FN4O3 Molecular Weight 450.51 Storage Store at -20°C  Targets VEGFR2/KDR c-Kit VEGFR3/FLT4 VEGFR1/FLT1 PDGFRβ IC50 0.5 nM 2 nM ≤3 nM ...

Wuhan Newbio Pharm-tech Co., Ltd.

Cediranib (Cas No.288383-20-0)
Cediranib (Cas No.288383-20-0)

Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3. ...

Shanghai Sun-shine bio-technology Co., Ltd