Rapamycin

FOB Price
USD $280.00 / Piece
Place Of Origin
Hubei, China
Minimum Order
100
Packaging
Aluminum Foil Bags or Fiber Drum.
Delivery
15 Days

99.6% High Purity Rapamycin/Sirolimus
(CAS: 53123-88-9)

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Chemical Information:
Quick Details:

Sirolimus CAS 53123-88-9 Brand: Newbio
MW: 914.172 MSDS: Avaiable
MF :C51H79NO13 Sample: Avaiable
Category: API Min order: 10grams
Quality standard: In-House Standard Place of Origin:China
Usage Sirolimus (INN/USAN), also known as rapamycin, is a macrolide produced by the bacteria Streptomyces hygroscopicus. It has immunosuppressant functions in humans and is used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T cells and B cells by inhibiting their response to interleukin-2 (IL-2). Sirolimus is also used as a coronary stent coating. Sirolimus works, in part, by eliminating old and abnormal white blood cells.[citation needed] Sirolimus is effective in mice with autoimmunity and in children with a rare condition called autoimmune lymphoproliferative syndrome (ALPS).
Applications Pharmaceutical raw materials

Product Name: Rapamycin
Other Names: AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM
Model No.: CUR-526
CAS No.: 53123-88-9
Molecular Formula: C51H79NO13
Molecular Weight: 914.18
Appearance: White or Nearly White Crystalline Powder
Purity: 99%+
Product Specifications: Pharmaceutical Grade
Standard: Qualified
MOQ(Minimum Order Quantity): 10g
Payment: L/C, T/T, Western Union
Shipment: EMS, DHL, FedEx,
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Packing: Aluminium Foil Bag or as Required
Origion: Hubei,China
Export Markets: Global
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Product Description:
Rapamycin (RAPA) is a new type of large ring lactone immunosuppressant. It is white solid crystal, melting point of 183-185 oC, lipophilic, soluble in methanol, ethanol, acetone, chloroform and other organic solvents, very slightly soluble in water, hardly soluble in ether. It was developed in the early 1970s, initially was as low toxicity antifungal drugs, and was found immunosuppressive in 1977. From 1989, RAPA was as a new drug for the treatment of organ transplantation rejection in trial, and from animal experiments and clinical application effects, it is of good curative effects, low toxicity and no new immunosuppressant nephrotoxicity. Now rapamycin is frequently as maintaining immunity drug for transplant organs (especially kidney transplant), to slow down the immune rejection of the organ in transplant surgery, however, scientists recently discovered another purpose: it can be used in the treatment of alzheimer's disease (senile dementia). To their interest, the main composition of rapamycin exists in Easter island isolated bacteria in the soil, and recent experiments show that the material used in the experimental rats can have ability to restore the memorization defects on the body.
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Applications/Usage:
1.Used as immunosuppressant.
2.A specific mTOR inhibitor with an IC50 of 0.1 nM.
3.Rapamycin is a triene macrolide discovered in 1995 as a metabolite of Streptomyces hygroscopicus found in a soil obtained on Rapi Nui (Easter Island).

FEATURED PRODUCT:
Wuhan Newbio Pharm-tech Co., Ltd.
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14 928672-86-0 Canagliflozin HemiHydrate 37 137281-23-3 Pemetrexed Disodium
15 41575-94-4 Carboplatin 38 53123-88-9 Rapamycin
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Rapamycin
Rapamycin

Product Name: Rapamycin Synonyms: AY 22989;23,27-EPOXY-3H-PYRIDO(2,1-C)(1,4)OXAAZACYCLOHENTRIACONTINE;NSC-226080;RAPA;RAPAMUNE;RAPAMYCIN;RAPAMYCIN, STREPTOMYCES HYGROSCOPICUS;RPM CAS: 53123-88-9 MF: C51H79NO13 MW: 914.18 EINECS: 262-640-9 Product Categories: Active ...

Yuancheng Group

Factory supply Rapamycin/sirolimus 98%/Ginkgo biloba extract/Anti-biotic
Factory supply Rapamycin/sirolimus 98%/Ginkgo biloba extract/Anti-biotic

Product Description Rapamycin Synonyms:23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine; Sirolimus Molecular Formula:C51H79NO13 Molecular Weight:914.18 CAS:53123-88-9 Application: Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, ...

Hunan World Well-Being Bio-tech Co.,Ltd.

Rapamycin (Sirolimus)  Cas: 53123-88-9
Rapamycin (Sirolimus) Cas: 53123-88-9

Quick Details ProName: Rapamycin (Sirolimus) Cas: 53123-88-9 Molecular Formula: C51H79NO13 Appearance: white powder Application: For Research Purity: 99.5%min Storage: Keep away from fire and heat Loss on drying:≤ 0.5% Heavy metals:≤ 0.002% Individual impurity:≤ 1.0% ...

Shanghai Oster Biotechnology Co.,Ltd