Methotrexate
Product Quick Detail
- FOB Price
- USD $280.00 / Piece
- Place Of Origin
- Hubei, China
- Minimum Order
- 100
- Packaging
- Aluminum Foil Bags or Fiber Drum.
- Delivery
- 15 Days
Specifications
High Quality Methotrexate with Good Price
(CAS 59-05-2)
Quick Details:
| Methotrexate | CAS : 59-05-2 | Brand: NEWBIO |
| MW: C20H22N8O5 | MSDS: Avaiable | |
| MF : 454.44 | Sample: Avaiable | |
| Category: Oncology drug | Min order: 10grams | |
| Quality standard: USP EP | Place of Origin:China | |
| Introduction | used as anti-tumour medicament. | |
| Character | Orange-yellow ,crystalline powder | |
| Applications | Pharmaceutical raw materials , Oncology drug |
Product Description:
Methotrexate is a cell cycle arresting agent with varying effects. Methotrexate arrests the cell cycle in late G1/S-phase, therefore inhibiting the synthesis of DNA, RNA, thymidylates, and proteins. In the previous cases the inhibition of enzymes involved in purine metabolism, leading to accumulation of adenosine, or the suppression of intercellular adhesion molecule expression by T cells as the main mechanism of action by methotrexate. The compound has been observed to irreversibly inhibit dihydrofolate reductase (DHFR) and thymidylate synthetase (TS). Methotrexate has been shown to modulate inflammation by promoting adenosine release or inhibiting transmethylation reactions. In adherent splenic cells, IL-1 production was decreased by methorexate.
COA:
| Text | USP27 | EP4 | BP2002 |
| Assay% | 98.0-102.0 | 98.0-102.0 | 98.0-102.0 |
| Residue on ignition% | â¤0.1 | ||
| Specific roataion | +19-+24 | +19-+24 | |
| Loss on drying% | |||
| Chromatographic purity% | â¤2.0(total) | ||
| â¤0.5(individual) | |||
| Water% | â¤12.0 | â¤13.0 | â¤12.0 |
| Organic Volatile impurites | conforms | ||
| Sulphated ash% | â¤0.1 | â¤0.1 | |
| Heavy metals ppm | 50 | 1 | |
| Related substance | |||
| Total | â¤1.3 | â¤1.3% | |
| Individual | At most five peaks | At most five peaks | |
| Impurity A% | â¤0.5 | â¤0.5 | |
| Impurity B% | â¤0.5 | â¤0.5 | |
| Impurity C% | â¤0.5 | â¤0.5 | |
| Impurity D% | â¤0.5 | â¤0.5 | |
| Impurity E% | â¤0.5 | â¤0.5 | |
| Unknown Impurity % | â¤0.5 | â¤0.5 | |
| (R)-Methotrexate% | â¤3.0 | â¤3.0 |
FEATURED PRODUCT:
| Wuhan Newbio Pharm-tech Co., Ltd. | |||||
| S# | CAS No. | Product Name | S# | CAS No. | Product Name |
| 1 | 86639-52-3 | 7-Ethyl-10-Hydroxycamptothecin | 25 | 183321-74-6 | Erlotinib |
| 2 | 154229-18-2 | Abiraterone Acetate | 26 | 183319-69-9 | Erlotinib Hydrochloride |
| 3 | 50-76-0 | Actinomycin D | 27 | 159351-69-6 | Everolimus |
| 4 | 106941-25-7 | Adefovir | 28 | 56296-78-7 | Fluoxetine Hydrochloride |
| 5 | 850140-72-6 | Afatinib | 29 | 184475-55-6 | Gefitinib Hydrochloride |
| 6 | 330784-47-9 | Avanafil | 30 | 136572-09-3 | Irinotecan Hydrochloride TriHydrate |
| 7 | 319460-85-0 | Axitinib | 31 | 1441674-54-9 | Ledipasvir(Acetone) |
| 8 | 1421373-66-1 | AZD-9291 (Mesylate) | 32 | 191732-72-6 | Lenalidomide |
| 9 | 123524-52-7 | Azelnidipine | 33 | 21672 | Methotrexate |
| 10 | 863031-21-4 | Azilsartan Medoxomil | 34 | 76144-81-5 | Mildronate |
| 11 | 179324-69-7 | Bortezomib | 35 | 474645-27-7 | Monomethyl Auristatin E |
| 12 | 357336-20-0 | Brivaracetam | 36 | 63121-00-6 | Oxaliplatin |
| 13 | 842133-18-0 | Canagliflozin | 49 | 33069-62-4 | Paclitaxel |
| 14 | 928672-86-0 | Canagliflozin HemiHydrate | 37 | 137281-23-3 | Pemetrexed Disodium |
| 15 | 41575-94-4 | Carboplatin | 38 | 53123-88-9 | Rapamycin |
| 16 | 50935-04-1 | Carubicin | 50 | 135062-02-1 | Repaglinide |
| 17 | 288383-20-0 | Cediranib | 39 | 945667-22-1 | Saxagliptin Hydrate |
| 18 | 15663-27-1 | Cisplatin | 40 | 709031-78-7 | Saxagliptin Hydrochloride |
| 19 | 877399-52-5 | Crizotinib | 41 | 486460-32-6 | Sitagliptin |
| 20 | 171500-79-1 | Dalbavancin | 42 | 654671-77-9 | Sitagliptin Phosphate Hydrate |
| 21 | 114977-28-5 | Docetaxel | 44 | 85622-93-1 | Temozolomide |
| 22 | 148408-66-6 | Docetaxel TriHydrate | 45 | 477600-75-2 | Tofacitinib |
| 23 | 25316-40-9 | Doxorubicin hydrochloride | 46 | 540737-29-9 | Tofacitinib Citrate |
| 24 | 133040-01-4 | Eprosartan | 47 | 170791-09-0 | Trityl Candesartan Cilexetil |
ABOUT DELIVERY:
#1 Products can be sent out within 24 hours after payment.
#2 Secure and discreet shipment.
#3 Various methods for your choice, like DHL/FedEx/SF-express.
OUR COMMITMENT:
#1 We are manufacturer with own factory and we sale this product at a best quality and low price.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
#2 All product listed is available in stock, please contact the sale for more details.
#3 We have QA&QC department to guarantees the quality, product pass rate can reach 100%.
CONTACT US:
| Telephone | +86-027-87002705 |
| Mobile | +86-13277093700 |
| newbiopharmtech | |
| FaceBook Page | https://www.facebook.com/newbiopharma/ |
| Facebook Group | https://www.facebook.com/groups/1739616069613416/ |
| Website | http://www.newbiopharm.com/ |
| Online Store | http://biocar.en.made-in-china.com/ |
If you want to source ...
#1 Pharmaceutical raw material,
#2 Oncology drug APIs,
#3 Antibiotics or fine chemicals,
We are a reliable manufacturer and supplier in China.
NEWBIO would like to ...
#1 We foucus on the high purity and high quality;
#2 We provide the raw materials at a good price;
#3 We have the best service and we are always there for you.
Please contact us for more infomation!!!
- Country: China (Mainland)
- Business Type:
- Market:
- Founded Year:2015
- Address:
- Contact:Jason Edwards
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