Recombinant Anti-CD20 x Anti-CD3 Bispecific Antibody (Tandem scFv) is designed to be expressed as a scFv from an anti-CD20 antibody variable domains fused with a scFv from an anti-CD3 antibody variable domains. It contains a His-tag at the C/N terminus for affinity ...
The anti-CD3/5T4 antibody targets CD3 and 5T4. The BiTE bispecific antibody can be potentially used for treating colon carcinoma via induction of T cell cytotoxicity. Targets5T4 & CD3 TypeBiTE Expression HostCHO Species ReactivityHuman Target 15T4 HostHuman Clone5T4-4 scFv (LH) ...
http://www.creativebiolabs.net/Bispecific-TPBG-CD3-antibody-35001.htm In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two ...
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor ...
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed ...
A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan ...
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the ...
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft ...