The human GRIN1/GRIN2B genes encode the cationic-selective, n-methyl-d-aspartic acid receptor-channel expressed in the CNS. NMDA receptors are therapeutic targets in treatment of neurological disorders including seizure, pain, and Alzheimer\"s disease. ...
The human GRIN1/GRIN2C genes encode an N-methyl-D-aspartate receptor belonging to the ionotropic glutamate receptor family. NMDA receptors expressed in neurons are therapeutic targets in treatment of neurological disorders. ...