Phenylalanine Ammonia-lyase

Country: United States
Market: Africa,Americas,Emerging Markets,Asia,European Union,Middle East
Founded Year: 2005
Address: 45-1 Ramsey Road Shirley
Contact: Lisa Clara

This enzyme is a member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.3 (histidine ammonia-lyase) and EC 4.3.1.23 (tyrosine ammonia-lyase) and EC 4.3.1.25 (phenylalanine/tyrosine ammonia-lyase). The enzyme contains the cofactor 3,5-dihydro-5-methylidene-4H-imidazol-4-one (MIO), which is common to this family. This unique cofactor is formed autocatalytically by cyclization and dehydration of the three amino-acid residues alanine, serine and glycine. The enzyme from some species is highly specific for phenylalanine.