Native Streptococcus Pyogenes Streptolysin O

Country: United States
Market: Africa,Americas,Emerging Markets,Asia,European Union,Middle East
Founded Year: 2005
Address: 45-1 Ramsey Road Shirley
Contact: Lisa Clara

Streptolysin O possesses a single polypeptide chain with a molecular weight of f62 kDa. Streptolysin O binds to membrane cholesterol and oligomerizes to create a ring structure that consists of 45 to 50 units. The ring structure inserts into the membrane to make a large pore (25 to 30 nm), which DNA, RNA, peptides and proteins may pass. It is thiol-activated. It is inhibited by allicin, an active component of garlic.