2-Ketoglutaric acid CAS:328-50-7

Place Of Origin
HuNan
Packaging
Foil Bag or Tin
Delivery
7 days
2-Ketoglutaric acid

Skype: yczht123456
ycgl08@yccreate.com

CAS:328-50-7
MF: C5H6O5
MW: 146.1
EINECS:206-330-3
Purity:99%
mp 113-115 °C

FEMA 3891

Functions:

Krebs cycle
α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. Anaplerotic reactions can replenish the cycle at this juncture by synthesizing α-ketoglutarate from transamination of glutamate, or through action of glutamate dehydrogenase on glutamate.

Formation of amino acids
Glutamine is synthesized from glutamate by glutamine synthetase, which utilizes an ATP to form glutamyl phosphate; this intermediate is attacked by ammonia as a nucleophile giving glutamine and inorganic phosphate.

Nitrogen transporter
Another function is to combine with nitrogen released in the cell, therefore preventing nitrogen overload.

α-Ketoglutarate is one of the most important nitrogen transporters in metabolic pathways. The amino groups of amino acids are attached to it (by transamination) and carried to the liver where the urea cycle takes place.

Dietary supplement
α-Ketoglutaric acids is sold as a dietary supplement and to body builders as AKG or a-KG with the claim that it improves peak athletic performance. This claim is based on studies that show excess ammonia in the body can combine with alpha-ketoglutarate, reducing problems associated with ammonia toxicity.However, the only studies that show alpha-ketoglutarate can reduce ammonia toxicity have been performed in hemodialysis patients.

Longevity
A study released on May 14, 2014 links α-ketoglutarate with significantly increased lifespan in nematode worms. Its anion, α-ketoglutarate (α-KG, also called oxo-glutarate) is an important biological compound. It is the keto acid produced by deamination of glutamate, and is an intermediate in the Krebs cycle.


Usage:
Determination of amino-converting enzyme dehydrogenase substrate reagents measuring liver function, also used as intermediates in organic synthesis. The main purpose as a sports nutrition beverage ingredients

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  • Founded Year:2013
  • Address:No.388 Huangshan Road, Tianyuan District, Zhuzhou City, Hunan Province,China
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2-Ketoglutaric Acid Hair Styling Agent 328-50-7
2-Ketoglutaric Acid Hair Styling Agent 328-50-7

Chemical Name: 2-Ketoglutaric acid Alternate names: alpha-Ketoglutaric acid, a-Ketoglutaric acid, alpha Ketoglutarate, 2-Oxoglutaric acid, 2-Oxopentanedioic acid; AKG CAS: 328-50-7 EC Number: 206-330-3 INCI Name: Ketoglutaric acid Mol Formula: C5H6O5 Mol Weight: 146.10 Packaging ...

Shenzhen BST Science & Technology Co., Ltd

2-Ketoglutaric acid
2-Ketoglutaric acid

Synonyms: 2-KETOGLUTARIC ACID;2-OXOGLUTARIC ACID;2-OXOPENTANEDIOIC ACID;A-KETOGLUTARIC ACID;ALPHA-KETOGLUTARIC ACID;GAMMA-KETOGLUTARIC ACID;FEMA 3891;KETO-GLU Product Details: Place of Origin: China Certification: ISO9001 Brand:YuanCheng Payment & Shipping Terms: Minimum Order ...

Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd.

2-Ketoglutaric acid  CAS:328-50-7
2-Ketoglutaric acid CAS:328-50-7

2-Ketoglutaric acid http://www.steroidsgym.com/ Skype: yczht123456 ycgl08@yccreate.com CAS:328-50-7 MF: C5H6O5 MW: 146.1 Purity:99% mp 113-115 °C Functions: Krebs cycle α-Ketoglutarate is a key intermediate in the Krebs cycle, coming after isocitrate and before succinyl CoA. ...

Zhuzhou Yuancheng Hezhong