Praziquantel
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Praziquantel
English Name: Praziquantel
CAS number: 55268-74-1
EINECS number: 259-559-6
Molecular formula: C19H24N2O2
Molecular weight: 312.41
Content: 99%
Packing: 25kg/ board barrel
Quality standard: USP36
Appearance: white or white crystalline powder, odorless, slightly bitter taste, hygroscopicity. Easy to be dissolved in two dimethyl sulfoxide.
The melting point of 136 to 141 DEG C.
Use:
1.Use of broad-spectrum anti parasitic drugs. For the treatment and prevention of schistosomiasis, cysticercosis, paragonimiasis, echinococcosis, Fasciolopsiasis, echinococcosis, worm infection.
2.Use as a vermifuge, effective on animal gastrointestinal nematodes. Can mix in feed use.
3.Use of the product is of Schistosoma japonicum, Schistosoma mansoni and S. haematobium, Clonorchis sinensis, paragonimiasis, Fasciolopsis and taeniasis and cysticercosis been effective anti worm
medicine. Especially strong killing effect on schistosomiasis tapeworms, is currently the best a middle fruit.
4.Use of anti worm medicine, mainly for schistosomiasis, also can be used for the Chinese branch of schistosomiasis, taeniasis and cysticercosis paragonimiasis, etc.
Production method of industrial production and various synthetic routes: isoquinoline route, piperazine route and phenylethylamine route, which better with quinoline route. Catalytic hydrogenation
by isoquinoline with benzoyl chloride and potassium cyanide addition, rearrangement of 1- benzoyl amino methyl -1, 2, 3, four 4- hydrogen isoquinoline, then by chloromethylation, cyclization,
pressurized hydrolysis, cyclohexyl acylation and.
Production method by using phenylethylamine as raw material, by acylation with chloroacetyl chloride, and then to two benzene carboxamide potassium amination reaction to introduce amino group, in
three phosphorus oxychloride role under the condition 3, 4- two hydrogen isoquinoline derivatives, 1- aminomethyl four tetrahydroquinoline obtained by hydrogenation, hydrolysis, successively with
cyclohexyl methyl chloride and chloroacetic chloride acylation, finally dehydrochlorination cyclizes to praziquantel.
Can also be isoquinoline as raw materials, through Reissert reaction, at the L position and introduction of cyano nitrogen benzoylation, then hydrogenation, while benzoyl transfer to the side chain
amino group, then in the ring on the amino introducing chloro acetyl, then cyclization, hydrolysis, cyclohexyl formylation to praziquantel.
- Country: China (Mainland)
- Business Type:
- Market:
- Founded Year:2010
- Address:No.496,Zhongshan Road, Wuhan, Hubei, China
- Contact:Cassie Lee
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CAS 55268-74-1 Praziquantel
Connect information: Nymeria Zhao E mail:ycsale11@chembj.com whatsapp:+8615315573717 Product Name: Praziquantel CAS: 55268-74-1 EINECS: 259-559-6 MF: C19H24N2O2 MW: 312.41 Assay: 99% Appearance: White powder standard:USP description: Praziquantel, marketed as Biltricide, is an ...
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CAS 55268-74-1 Praziquantel Product Name: Praziquantel CAS: 55268-74-1 EINECS: 259-559-6 MF: C19H24N2O2 MW: 312.41 Assay: 99% Appearance: White powder Praziquantel, marketed as Biltricide, is an anthelmintic used in humans and animals for the treatment of tapeworms and flukes. ...
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