PLX647 was tested against a panel of 400 kinases at a concentration of 1 μM, 35-fold above its FMS enzymatic IC50 and 60-fold above its KIT enzymatic IC50. In addition to FMS and KIT, the activities of only nine kinases were inhibited by more than 50%. PLX647 potently inhibits t
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 11:01:11 ]
AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:58:04 ]
2,3,5-trichloropyridine Name 2,3,5-trichloropyridine Synonym 2,3,5-trichloro-pyridin;2,3,5-TRICHLOROPYRIDINE;Trichloropyridine,98%;2,3,5-TRICHLOROPYRIDINE 98+%;3,5,6-Trichloropyridine;Pyridine, 2,3,5-trichloro-;5-Trichloropyridine CAS 16063-70-0 EINECS 407-270-2 Assay 98% M F C5H
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:57:08 ]
2,3,5,6-Tetrafluorophenol CAS 769-39-1 MF C6H2F4O MW 166.07 EINECS 212-209-6 mp 37-39 °C(lit.) bp 140 °C(lit.) Chemical Properties white solid Purity 99% Usage API Package 1KG foil bag; 25Kg drum Price us$1666
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:56:16 ]
2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Name 2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE Synonym 2,2,5,5-Tetramethyldihydro-3(2H)-furanone;3(2H)-Furanone,dihydro-2,2,5,5-tetramethyl-;DIHYDRO-2,2,5,5-TETRAMETHYL-3(2H)-FURANONE;2,2,5,5-TETRAMETHYLTETRAHYDROFURAN-3-ONE;2,2,5,5-Tetrame
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:54:48 ]
Indazole-3-carboxylic acid CAS 4498-67-3 MF C8H6N2O2 MW 162.15 EINECS 224-794-5 mp 266-270 °C (dec.) storage temp. Refrigerator Chemical Properties yellow crystal Usage Indole derivatives useful in treatment of pain and inflammation Purity 99% Usage API Package 1KG foil bag; 25K
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:53:16 ]
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:53:10 ]
16 Alpha Hydroxprednisolone Synonyms 11a,16b,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione CAS 13951-70-7 MF C21H28O6 MW 376.44 EINECS 237-731-1 mp 235-238°C storage temp. -20°C Freezer Chemical Properties White Crystalline Solid Usage A metabolite of Budesonide, an antiinflam
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:52:39 ]
Tricyclo[3.3.1.13,7]decane-1-carboxylicacid Name Tricyclo[3.3.1.13,7]decane-1-carboxylicacid EINECS 212-584-6 Molecular Formula C11H16O2 CAS 828-51-3 Synonyms 1-Adamantanecarboxylicacid (6CI,7CI,8CI); 1-Adamantane-1-carboxylic acid; 1-Carboxyadamantane; Adamantoic acid; 1-Admant
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:51:17 ]
Name 1-PHENYLPIPERAZINE MONOHYDROCHLORIDE Synonym 1-PHENYLPIPERAZINE HYDROCHLORIDE 1-PHENYLPIPERAZINE HYDROCHLORIDE (1 1) 1-PHENYLPIPERAZINIUM CHLORIDE CAS 2210-93-7 EINECS 218-646-9 Assay 98% M F C10H15ClN2 M W 198.69 MP 247-250 oC BP 287.2℃ at 760 mmHg Appearance white crysta
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:50:25 ]
APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:50:07 ]
1-Phenylmethyl-5-phenyl-barbituric acid Name 1-Phenylmethyl-5-phenyl-barbituric acid Synonym 1-PHENYLMETHYL-5-PHENYL-BARBITURIC ACID;1-BENZYL-5-PHENYLBARBITURIC ACID;BENZYL-5-PHENYLBARBITURIC ACID;LABOTEST-BB LT00454619;6(1h,3h,5h)-pyrimidinetrione,5-phenyl-1-(phenylmethyl)-4;1-B
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:49:34 ]
1-Piperazinamine,4-methyl- Name 1-Piperazinamine,4-methyl- EINECS 230-053-7 Molecular Formula C5H13N3 CAS 6928-85-4 Synonyms Piperazine,1-amino-4-methyl- (6CI,7CI,8CI); (4-Methylpiperazin-1-yl)amine; 1-Methyl-4-aminopiperazine; 4-Methyl-1-aminopiperazine; N-Amino-N'-methylpipera
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:48:18 ]
Terbutaline sulfate is a β2-adrenergic receptor agonist; a fast-acting bronchodilator and a tocolytic to delay premature labor.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:46:28 ]
1-Bromo-3,5-dimethyladamantane CAS 941-37-7 MF C12H19Br MW 243.18 EINECS 213-378-9 bp 201 °C(lit.) density 1.224 g/mL at 25 °C(lit.) refractive index n20/D 1.52(lit.) Fp 228 °F storage temp. Refrigerator Chemical Properties Clear Colorless Oil Purity 99% Usage API Package 1KG
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:45:59 ]
1-(4-Nitrophenyl)piperazine Name 1-(4-Nitrophenyl)piperazine Synonym Piperazine, 1-(4-nitrophenyl)-;N-(4-NITROPHENYL)PIPERAZINE;RARECHEM AH CK 0146;TIMTEC-BB SBB003475;AKOS BBS-00003599;1-(P-NITROPHENYL)PIPERAZINE;1-NITRO-4-(1-PIPERAZINYL)BENZENE;1-(4-NITROPHENYL)PIPERAZINE CAS 6
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:43:54 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt) , EGFR(L858R) , EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM in cell-free assays, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:42:45 ]
1-(2,6-DICHLOROPHENYL)-2-INDOLINONE Name 1-(2,6-DICHLOROPHENYL)-2-INDOLINONE Synonym 1-(2,6-DICHLOROPHENYL)INDOLIN-2-ONE 1-(2, 6-DICHLOROPHENYL)-2-INDOLINONE CAS 15362-40-0 EINECS 239-399-3 Assay 99% M F C14H9Cl2NO M W 278.14 MP 115-119°C Application As the drug diclofenac inter
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:42:27 ]
1,6-Hexanediamine,hydrochloride (1 2) Name 1,6-Hexanediamine,hydrochloride (1 2) EINECS 204-679-6 Molecular Formula C6H16 N2 . 2 Cl H CAS 6055-52-3 Synonyms 1,6-Hexanediamine,dihydrochloride (8CI,9CI); 1,6-Diaminohexane dihydrochloride; 1,6-Hexamethylenediamine dihydrochloride;
Hubei YuanCheng GongChuang Technology Co.Ltd [2015-06-03 10:40:42 ]
Afatinib (BIBW2992) irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively; 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant.
Shanghai Sun-shine bio-technology Co., Ltd [2015-06-03 10:39:48 ]
